Application of heparin-binding protein detection in respiratory infectious diseases
The bactericidal ability of HBP as well as the heparin-binding ability are related to its strong positive charge. HBP, as a chemotactic substance, can activate monocytes and macrophages, induce vascular leakage and tissue edema. Inactivating HBP blocks endothelial hyperosmocyte hyperpermeability caused by neutrophils. At present, HBP, as an acute phase protein, is an effective biomarker to assess the severity of disease in patients with sepsis, and is more important in the early diagnosis and efficacy monitoring of patients with septic shock. In recent years, several studies have shown that in addition to being used in the early diagnosis of sepsis, high quality Clinical Chemistry HBP Reagent Kit has certain clinical significance in the diagnosis and prediction of respiratory diseases. HBP, PCT, CRP poct rapid test all have certain predictive significance for AECOPD, and HBP has the best prediction results. In patients with thick sputum or requiring mechanical ventilation who w